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The Molecular Basis of Drug Addiction: Linking Epigenetic to Synaptic and Circuit Mechanisms

Addiction is a disease in which, after a period of recreational use, a subset of individuals develops compulsive use that does not stop even in light of major negative consequences. Here, we review the evidence for underlying epigenetic remodeling in brain in two settings. First, excessive dopamine...

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Bibliografische gegevens
Gepubliceerd in:Neuron
Hoofdauteurs: Nestler, Eric J., Lüscher, Christian
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2019
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6587180/
https://ncbi.nlm.nih.gov/pubmed/30946825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2019.01.016
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