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Drug-evoked synaptic plasticity in addiction: from molecular changes to circuit remodeling

Addictive drugs have in common that they target the mesocoticolimbic dopamine (DA) system. This system originates in the ventral tegmental area (VTA) and projects mainly to the nucleus accumbens (NAc) and prefrontal cortex (PFC). Here we review the effects that such drugs leave on glutamatergic and...

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Autors principals: Lüscher, Christian, Malenka, Robert C.
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4046255/
https://ncbi.nlm.nih.gov/pubmed/21338877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2011.01.017
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