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Drug-evoked plasticity: do addictive drugs reopen a critical period of postnatal synaptic development?

As in other parts of the central nervous system (CNS) of the mouse, glutamatergic synapses onto dopamine (DA) neurons in the ventral tegmental area (VTA) mature postnatally. At birth many AMPA receptors (AMPARs) lack GluA2R subunit and most NMDARs contain the GluN2B subunit. Within 2 weeks these rec...

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Détails bibliographiques
Auteurs principaux: Bellone, Camilla, Lüscher, Christian
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3375625/
https://ncbi.nlm.nih.gov/pubmed/22715323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2012.00075
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