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Drug-evoked plasticity: do addictive drugs reopen a critical period of postnatal synaptic development?

As in other parts of the central nervous system (CNS) of the mouse, glutamatergic synapses onto dopamine (DA) neurons in the ventral tegmental area (VTA) mature postnatally. At birth many AMPA receptors (AMPARs) lack GluA2R subunit and most NMDARs contain the GluN2B subunit. Within 2 weeks these rec...

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Autori principali: Bellone, Camilla, Lüscher, Christian
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3375625/
https://ncbi.nlm.nih.gov/pubmed/22715323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2012.00075
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