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In-silico Prediction of Synergistic Anti-Cancer Drug Combinations Using Multi-omics Data

Chemotherapy is a routine treatment approach for early-stage cancers, but the effectiveness of such treatments is often limited by drug resistance, toxicity, and tumor heterogeneity. Combination chemotherapy, in which two or more drugs are applied simultaneously, offers one promising approach to add...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Celebi, Remzi, Bear Don’t Walk, Oliver, Movva, Rajiv, Alpsoy, Semih, Dumontier, Michel
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6586895/
https://ncbi.nlm.nih.gov/pubmed/31222109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-45236-6
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