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In-silico Prediction of Synergistic Anti-Cancer Drug Combinations Using Multi-omics Data

Chemotherapy is a routine treatment approach for early-stage cancers, but the effectiveness of such treatments is often limited by drug resistance, toxicity, and tumor heterogeneity. Combination chemotherapy, in which two or more drugs are applied simultaneously, offers one promising approach to add...

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Publicat a:Sci Rep
Autors principals: Celebi, Remzi, Bear Don’t Walk, Oliver, Movva, Rajiv, Alpsoy, Semih, Dumontier, Michel
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6586895/
https://ncbi.nlm.nih.gov/pubmed/31222109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-45236-6
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