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Characterization of C-nucleoside Antimicrobials from Streptomyces albus DSM 40763: Strepturidin is Pseudouridimycin

Pseudouridimycin (PUM), a selective inhibitor of bacterial RNA polymerase has been previously detected in microbial-extracts of two strains of Streptomyces species (strain ID38640 and ID38673). Here, we isolated PUM and its deoxygenated analogue desoxy-pseudouridimycin (dPUM) from Streptomyces albus...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Rosenqvist, Petja, Palmu, Kaisa, Prajapati, Ranjit Kumar, Yamada, Keith, Niemi, Jarmo, Belogurov, Georgiy A., Metsä-Ketelä, Mikko, Virta, Pasi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6586884/
https://ncbi.nlm.nih.gov/pubmed/31222036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-45375-w
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