Substrate-induced conformational dynamics of the dopamine transporter

The dopamine transporter is a member of the neurotransmitter:sodium symporters (NSSs), which are responsible for termination of neurotransmission through Na(+)-driven reuptake of neurotransmitter from the extracellular space. Experimental evidence elucidating the coordinated conformational rearrange...

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Udgivet i:Nat Commun
Main Authors: Nielsen, Anne Kathrine, Möller, Ingvar R., Wang, Yong, Rasmussen, Søren G. F., Lindorff-Larsen, Kresten, Rand, Kasper D., Loland, Claus J.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6586795/
https://ncbi.nlm.nih.gov/pubmed/31221956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10449-w
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