miR-200c Prevents TGF-β1-Induced Epithelial-to-Mesenchymal Transition and Fibrogenesis in Mesothelial Cells by Targeting ZEB2 and Notch1

Peritoneal fibrosis and loss of transport function is a common complication contributing to adverse outcomes in patients on long-term peritoneal dialysis (PD). Epithelial-to-mesenchymal transition (EMT) in mesothelial cells is a salient feature, but its triggering mechanisms remain obscure. Dysregul...

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Detalhes bibliográficos
Publicado no:Mol Ther Nucleic Acids
Main Authors: Chu, Jessica Y.S., Chau, Mel K.M., Chan, Caleb C.Y., Tai, Andrew C.P., Cheung, Kwok Fan, Chan, Tak Mao, Yung, Susan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6586597/
https://ncbi.nlm.nih.gov/pubmed/31226520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2019.05.008
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