Increased cerebral vascularization and decreased water exchange across the blood-brain barrier in aquaporin-4 knockout mice

Aquaporin-4 (AQP4) plays an important role in regulating water exchange across the blood-brain barrier (BBB) and brain-cerebrospinal fluid interface. Studies on AQP-4 knockout mice (AQP4-KO) have reported considerable protection from brain edema induced by acute water intoxication and ischemic strok...

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Udgivet i:PLoS One
Main Authors: Zhang, Yifan, Xu, Kui, Liu, Yuchi, Erokwu, Bernadette O., Zhao, Pan, Flask, Chris A., Ramos-Estebanez, Ciro, Farr, George W., LaManna, Joseph C., Boron, Walter F., Yu, Xin
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6586297/
https://ncbi.nlm.nih.gov/pubmed/31220136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0218415
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