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Functionalized Phenylbenzamides Inhibit Aquaporin-4 Reducing Cerebral Edema and Improving Outcome in Two Models of CNS Injury

Cerebral edema in ischemic stroke can lead to increased intracranial pressure, reduced cerebral blood flow and neuronal death. Unfortunately, current therapies for cerebral edema are either ineffective or highly invasive. During the development of cytotoxic and subsequent ionic cerebral edema water...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Neuroscience
Päätekijät: Farr, George W, Hall, Christopher H, Farr, Susan M, Wade, Ramon, Detzel, Joshua M, Adams, Amielia G, Buch, Jasen M, Beahm, Derek L, Flask, Christopher A, Xu, Kui, LaManna, Joseph C, McGuirk, Paul R, Boron, Walter F, Pelletier, Marc F
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6495193/
https://ncbi.nlm.nih.gov/pubmed/30738082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2019.01.034
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