Treatment Potential for Macular Cone Vision in Leber Congenital Amaurosis Due to CEP290 or NPHP5 Mutations: Predictions From Artificial Intelligence

PURPOSE: To use supervised machine learning to predict visual function from retinal structure in retinitis pigmentosa (RP) and apply these estimates to CEP290- and NPHP5-associated Leber congenital amaurosis (LCA) to determine the potential for functional improvement. METHODS: Patients with RP (n =...

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Publicado en:Invest Ophthalmol Vis Sci
Autores principales: Sumaroka, Alexander, Garafalo, Alexandra V., Semenov, Evelyn P., Sheplock, Rebecca, Krishnan, Arun K., Roman, Alejandro J., Jacobson, Samuel G., Cideciyan, Artur V.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Association for Research in Vision and Ophthalmology 2019
Materias:
Retina
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6586080/
https://ncbi.nlm.nih.gov/pubmed/31212307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.19-27156
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