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Data Curation can Improve the Prediction Accuracy of Metabolic Intrinsic Clearance
A key consideration at the screening stages of drug discovery is in vitro metabolic stability, often measured in human liver microsomes. Computational prediction models can be built using a large quantity of experimental data available from public databases, but these databases typically contain dat...
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| Yayımlandı: | Mol Inform |
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| Asıl Yazarlar: | , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
John Wiley and Sons Inc.
2018
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6586005/ https://ncbi.nlm.nih.gov/pubmed/30247811 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/minf.201800086 |
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