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Developing a Kinase-Specific Target Selection Method Using a Structure-Based Machine Learning Approach
INTRODUCTION: Despite recent advances in the drug discovery field, developing selective kinase inhibitors remains a complicated issue for a number of reasons, one of which is that there are striking structural similarities in the ATP-binding pockets of kinases. OBJECTIVE: To address this problem, we...
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| Pubblicato in: | Adv Appl Bioinform Chem |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Dove
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7719317/ https://ncbi.nlm.nih.gov/pubmed/33293834 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/AABC.S278900 |
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