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Developing a Kinase-Specific Target Selection Method Using a Structure-Based Machine Learning Approach
INTRODUCTION: Despite recent advances in the drug discovery field, developing selective kinase inhibitors remains a complicated issue for a number of reasons, one of which is that there are striking structural similarities in the ATP-binding pockets of kinases. OBJECTIVE: To address this problem, we...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Adv Appl Bioinform Chem |
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| Κύριοι συγγραφείς: | , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Dove
2020
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7719317/ https://ncbi.nlm.nih.gov/pubmed/33293834 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/AABC.S278900 |
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