A Versatile and Convenient Synthesis of (34)S‐Labeled Phosphorothioate Oligonucleotides

A synthetic protocol for (34)S‐labeled phosphorothioate oligonucleotides (PS ONs) was developed to facilitate MS‐based assay analysis. This was enabled by a highly efficient, two‐step, one‐pot synthesis of (34)S‐labeled phenylacetyl disulfide ((34)S‐PADS), starting from (34)S‐enriched elemental sulf...

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Bibliografiske detaljer
Udgivet i:Chembiochem
Main Authors: Stulz, Rouven, Meuller, Johan, Baždarević, Dženita, Wennberg Huldt, Charlotte, Strömberg, Roger, Andersson, Shalini, Dahlén, Anders
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2018
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Full Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6585993/
https://ncbi.nlm.nih.gov/pubmed/30062829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201800417
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