Laddar...
Phosphorothioate Oligonucleotides Block the VDAC Channel
Proapoptotic phosphorothioate oligonucleotides such as G3139 (an 18-mer) induce Bcl-2-independent apoptosis, perhaps partly via direct interaction with VDAC and reduction of metabolite flow across the mitochondrial outer membrane. Here, we analyzed the interactions at the molecular level. Ten microm...
Sparad:
| Huvudupphovsmän: | , , , , |
|---|---|
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
The Biophysical Society
2007
|
| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1929033/ https://ncbi.nlm.nih.gov/pubmed/17483171 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.105379 |
| Taggar: |
Lägg till en tagg
Inga taggar, Lägg till första taggen!
|