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Population Pharmacokinetics and Exposure‐Response Relationship of Intravenous and Subcutaneous Abatacept in Patients With Rheumatoid Arthritis

Abatacept population pharmacokinetics (PK) and exposure‐response (E‐R) models for selective efficacy end points were developed using phase 2 and 3 study data in patients with rheumatoid arthritis treated with abatacept (intravenous [IV] or subcutaneous [SC]), followed by simulations. Two efficacy en...

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Dades bibliogràfiques
Publicat a:J Clin Pharmacol
Autors principals: Li, Xiaohui, Roy, Amit, Murthy, Bindu
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6585965/
https://ncbi.nlm.nih.gov/pubmed/30229926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcph.1308
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