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Bioequivalence of Olanzapine Given in Combination With Samidorphan as a Bilayer Tablet (ALKS 3831) Compared With Olanzapine‐Alone Tablets: Results From a Randomized, Crossover Relative Bioavailability Study

The objective of this study was to evaluate the relative bioavailability of olanzapine in 3 olanzapine‐containing tablet formulations. ALKS 3831 is a fixed‐dose combination of olanzapine (OLZ, an atypical antipsychotic) and samidorphan (SAM, a μ‐opioid receptor antagonist with low intrinsic activity...

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Detalhes bibliográficos
Publicado no:Clin Pharmacol Drug Dev
Main Authors: Sun, Lei, McDonnell, David, Liu, Jianjun, von Moltke, Lisa
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6585851/
https://ncbi.nlm.nih.gov/pubmed/30059196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpdd.601
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