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Delivery Aspects of CRISPR/Cas for in Vivo Genome Editing

[Image: see text] The discovery of CRISPR/Cas has revolutionized the field of genome editing. CRIPSR/Cas components are part of the bacterial immune system and are able to induce double-strand DNA breaks in the genome, which are resolved by endogenous DNA repair mechanisms. The most relevant of thes...

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Publicat a:Acc Chem Res
Autors principals: Wilbie, Danny, Walther, Johanna, Mastrobattista, Enrico
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2019
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6584901/
https://ncbi.nlm.nih.gov/pubmed/31099553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.accounts.9b00106
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