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Transcriptomic analysis reveals cell apoptotic signature modified by heparanase in melanoma cells

Heparanase has been implicated in many pathological conditions, especially inflammation and cancer, attributed to its degradation of heparan sulfate, a crucial component maintaining the integrity of the extracellular matrix. By silencing the heparanase gene (HPSE) in MDA‐MB‐435s melanoma cells, we i...

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Bibliographic Details
Published in:J Cell Mol Med
Main Authors: Song, Tianyi, Spillmann, Dorothe
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6584584/
https://ncbi.nlm.nih.gov/pubmed/31044520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14349
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