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Transcriptomic analysis reveals cell apoptotic signature modified by heparanase in melanoma cells

Heparanase has been implicated in many pathological conditions, especially inflammation and cancer, attributed to its degradation of heparan sulfate, a crucial component maintaining the integrity of the extracellular matrix. By silencing the heparanase gene (HPSE) in MDA‐MB‐435s melanoma cells, we i...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Song, Tianyi, Spillmann, Dorothe
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6584584/
https://ncbi.nlm.nih.gov/pubmed/31044520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14349
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