PAR-4 overcomes chemo-resistance in breast cancer cells by antagonizing cIAP1

Most deaths from breast cancer result from tumour recurrence, which is typically an incurable disease. Down-regulation of the pro-apoptotic tumour suppressor protein prostate apoptosis response-4 (PAR-4) is required for breast cancer recurrence and resistance to chemotherapy. Recent advances in the...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Guo, Haihong, Treude, Fabian, Krämer, Oliver H., Lüscher, Bernhard, Hartkamp, Jörg
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6584570/
https://ncbi.nlm.nih.gov/pubmed/31217499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-45209-9
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