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Role of synergy and immunostimulation in design of chemotherapy combinations: An analysis of doxorubicin and camptothecin

Combination chemotherapy is often employed to improve therapeutic efficacies of drugs. However, traditional combination regimens often utilize drugs at or near‐their maximum tolerated doses (MTDs), elevating the risk of dose‐related toxicity and impeding their clinical success. Further, high doses o...

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Bibliografiska uppgifter
I publikationen:Bioeng Transl Med
Huvudupphovsmän: Pusuluri, Anusha, Krishnan, Vinu, Wu, Debra, Shields, C. Wyatt, Wang, Li W., Mitragotri, Samir
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley & Sons, Inc. 2019
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6584462/
https://ncbi.nlm.nih.gov/pubmed/31249879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/btm2.10129
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