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Role of synergy and immunostimulation in design of chemotherapy combinations: An analysis of doxorubicin and camptothecin

Combination chemotherapy is often employed to improve therapeutic efficacies of drugs. However, traditional combination regimens often utilize drugs at or near‐their maximum tolerated doses (MTDs), elevating the risk of dose‐related toxicity and impeding their clinical success. Further, high doses o...

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Detalhes bibliográficos
Publicado no:Bioeng Transl Med
Main Authors: Pusuluri, Anusha, Krishnan, Vinu, Wu, Debra, Shields, C. Wyatt, Wang, Li W., Mitragotri, Samir
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6584462/
https://ncbi.nlm.nih.gov/pubmed/31249879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/btm2.10129
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