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Role of synergy and immunostimulation in design of chemotherapy combinations: An analysis of doxorubicin and camptothecin

Combination chemotherapy is often employed to improve therapeutic efficacies of drugs. However, traditional combination regimens often utilize drugs at or near‐their maximum tolerated doses (MTDs), elevating the risk of dose‐related toxicity and impeding their clinical success. Further, high doses o...

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Détails bibliographiques
Publié dans:Bioeng Transl Med
Auteurs principaux: Pusuluri, Anusha, Krishnan, Vinu, Wu, Debra, Shields, C. Wyatt, Wang, Li W., Mitragotri, Samir
Format: Artigo
Langue:Inglês
Publié: John Wiley & Sons, Inc. 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6584462/
https://ncbi.nlm.nih.gov/pubmed/31249879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/btm2.10129
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