Effect of Low-Dose Intracoronary Alteplase During Primary Percutaneous Coronary Intervention on Microvascular Obstruction in Patients With Acute Myocardial Infarction: A Randomized Clinical Trial

IMPORTANCE: Microvascular obstruction commonly affects patients with acute ST-segment elevation myocardial infarction (STEMI) and is associated with adverse outcomes. OBJECTIVE: To determine whether a therapeutic strategy involving low-dose intracoronary fibrinolytic therapy with alteplase infused e...

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Bibliografiske detaljer
Udgivet i:JAMA
Main Authors: McCartney, Peter J., Eteiba, Hany, Maznyczka, Annette M., McEntegart, Margaret, Greenwood, John P., Muir, Douglas F., Chowdhary, Saqib, Gershlick, Anthony H., Appleby, Clare, Cotton, James M., Wragg, Andrew, Curzen, Nick, Oldroyd, Keith G., Lindsay, Mitchell, Rocchiccioli, J. Paul, Shaukat, Aadil, Good, Richard, Watkins, Stuart, Robertson, Keith, Malkin, Christopher, Martin, Lynn, Gillespie, Lynsey, Ford, Thomas J., Petrie, Mark C., Macfarlane, Peter W., Tait, R. Campbell, Welsh, Paul, Sattar, Naveed, Weir, Robin A., Fox, Keith A., Ford, Ian, McConnachie, Alex, Berry, Colin
Format: Artigo
Sprog:Inglês
Udgivet: American Medical Association 2019
Fag:
Original Investigation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6583564/
https://ncbi.nlm.nih.gov/pubmed/30620371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.2018.19802
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