Effect of Low-Dose Intracoronary Alteplase During Primary Percutaneous Coronary Intervention on Microvascular Obstruction in Patients With Acute Myocardial Infarction: A Randomized Clinical Trial

IMPORTANCE: Microvascular obstruction commonly affects patients with acute ST-segment elevation myocardial infarction (STEMI) and is associated with adverse outcomes. OBJECTIVE: To determine whether a therapeutic strategy involving low-dose intracoronary fibrinolytic therapy with alteplase infused e...

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Bibliografske podrobnosti
izdano v:JAMA
Main Authors: McCartney, Peter J., Eteiba, Hany, Maznyczka, Annette M., McEntegart, Margaret, Greenwood, John P., Muir, Douglas F., Chowdhary, Saqib, Gershlick, Anthony H., Appleby, Clare, Cotton, James M., Wragg, Andrew, Curzen, Nick, Oldroyd, Keith G., Lindsay, Mitchell, Rocchiccioli, J. Paul, Shaukat, Aadil, Good, Richard, Watkins, Stuart, Robertson, Keith, Malkin, Christopher, Martin, Lynn, Gillespie, Lynsey, Ford, Thomas J., Petrie, Mark C., Macfarlane, Peter W., Tait, R. Campbell, Welsh, Paul, Sattar, Naveed, Weir, Robin A., Fox, Keith A., Ford, Ian, McConnachie, Alex, Berry, Colin
Format: Artigo
Jezik:Inglês
Izdano: American Medical Association 2019
Teme:
Original Investigation
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6583564/
https://ncbi.nlm.nih.gov/pubmed/30620371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.2018.19802
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