Effect of Low-Dose Intracoronary Alteplase During Primary Percutaneous Coronary Intervention on Microvascular Obstruction in Patients With Acute Myocardial Infarction: A Randomized Clinical Trial

IMPORTANCE: Microvascular obstruction commonly affects patients with acute ST-segment elevation myocardial infarction (STEMI) and is associated with adverse outcomes. OBJECTIVE: To determine whether a therapeutic strategy involving low-dose intracoronary fibrinolytic therapy with alteplase infused e...

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Detalhes bibliográficos
Publicado no:JAMA
Main Authors: McCartney, Peter J., Eteiba, Hany, Maznyczka, Annette M., McEntegart, Margaret, Greenwood, John P., Muir, Douglas F., Chowdhary, Saqib, Gershlick, Anthony H., Appleby, Clare, Cotton, James M., Wragg, Andrew, Curzen, Nick, Oldroyd, Keith G., Lindsay, Mitchell, Rocchiccioli, J. Paul, Shaukat, Aadil, Good, Richard, Watkins, Stuart, Robertson, Keith, Malkin, Christopher, Martin, Lynn, Gillespie, Lynsey, Ford, Thomas J., Petrie, Mark C., Macfarlane, Peter W., Tait, R. Campbell, Welsh, Paul, Sattar, Naveed, Weir, Robin A., Fox, Keith A., Ford, Ian, McConnachie, Alex, Berry, Colin
Formato: Artigo
Idioma:Inglês
Publicado em: American Medical Association 2019
Assuntos:
Original Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6583564/
https://ncbi.nlm.nih.gov/pubmed/30620371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.2018.19802
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