Association Between Longitudinal Plasma Neurofilament Light and Neurodegeneration in Patients With Alzheimer Disease

IMPORTANCE: Plasma neurofilament light (NfL) has been suggested as a noninvasive biomarker to monitor neurodegeneration in Alzheimer disease (AD), but studies are lacking. OBJECTIVE: To examine whether longitudinal plasma NfL levels are associated with other hallmarks of AD. DESIGN, SETTING, AND PAR...

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Опубликовано в: :JAMA Neurol
Главные авторы: Mattsson, Niklas, Cullen, Nicholas C., Andreasson, Ulf, Zetterberg, Henrik, Blennow, Kaj
Формат: Artigo
Язык:Inglês
Опубликовано: American Medical Association 2019
Предметы:
Original Investigation
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6583067/
https://ncbi.nlm.nih.gov/pubmed/31009028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2019.0765
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