Long-term Survival and Value of Chimeric Antigen Receptor T-Cell Therapy for Pediatric Patients With Relapsed or Refractory Leukemia

IMPORTANCE: Among children and young adults with relapsed or refractory B-cell acute lymphoblastic leukemia, the rate of 5-year disease-free survival is 10% to 20%. Approval of tisagenlecleucel, a chimeric antigen receptor T-cell therapy, represents a new and potentially curative treatment option. H...

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Detalhes bibliográficos
Publicado no:JAMA Pediatr
Main Authors: Whittington, Melanie D., McQueen, R. Brett, Ollendorf, Daniel A., Kumar, Varun M., Chapman, Richard H., Tice, Jeffrey A., Pearson, Steven D., Campbell, Jonathan D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Medical Association 2018
Assuntos:
Original Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6583018/
https://ncbi.nlm.nih.gov/pubmed/30304407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamapediatrics.2018.2530
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