Impact of Integrase Inhibition Compared With Nonnucleoside Inhibition on HIV Reservoirs in Lymphoid Tissues

BACKGROUND: HIV is produced in lymphoid tissues (LT) and stored on the follicular dendritic cell network in LT. When antiretroviral therapy is started, plasma viremia decays in 2 phases; the first within days of starting therapy and the second over weeks. Raltegravir (RAL), an integrase inhibitor, h...

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Bibliografische gegevens
Gepubliceerd in:J Acquir Immune Defic Syndr
Hoofdauteurs: Rothenberger, Meghan, Nganou-Makamdop, Krystelle, Kityo, Cissy, Ssali, Francis, Chipman, Jeffrey G., Beilman, Gregory J., Hoskuldsson, Torfi, Anderson, Jodi, Jasurda, Jake, Schmidt, Thomas E., Calisto, Samuel P., Pearson, Hope, Reimann, Thomas, David, Caitlin, Perkey, Katherine, Southern, Peter, Wietgrefe, Steve, Helgeson, Erika, Reilly, Cavan, Haase, Ashley T., Douek, Daniel C, Fletcher, Courtney V., Schacker, Timothy W.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: JAIDS Journal of Acquired Immune Deficiency Syndromes 2019
Onderwerpen:
Translational Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6582649/
https://ncbi.nlm.nih.gov/pubmed/31192893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0000000000002026
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