Lymphoid tissue fibrosis is associated with impaired vaccine responses

Vaccine responses vary by geographic location. We have previously described how HIV-associated inflammation leads to fibrosis of secondary lymph nodes (LNs) and T cell depletion. We hypothesized that other infections may cause LN inflammation and fibrosis, in a process similar to that seen in HIV in...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Kityo, Cissy, Makamdop, Krystelle Nganou, Rothenberger, Meghan, Chipman, Jeffrey G., Hoskuldsson, Torfi, Beilman, Gregory J., Grzywacz, Bartosz, Mugyenyi, Peter, Ssali, Francis, Akondy, Rama S., Anderson, Jodi, Schmidt, Thomas E., Reimann, Thomas, Callisto, Samuel P., Schoephoerster, Jordan, Schuster, Jared, Muloma, Proscovia, Ssengendo, Patrick, Moysi, Eirini, Petrovas, Constantinos, Lanciotti, Ray, Zhang, Lin, Arévalo, Maria T., Rodriguez, Benigno, Ross, Ted M., Trautmann, Lydie, Sekaly, Rafick-Pierre, Lederman, Michael M., Koup, Richard A., Ahmed, Rafi, Reilly, Cavan, Douek, Daniel C., Schacker, Timothy W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6025977/
https://ncbi.nlm.nih.gov/pubmed/29781814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI97377
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