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Synaptic FUS Localization During Motoneuron Development and Its Accumulation in Human ALS Synapses
Mutations in the fused in Sarcoma (FUS) gene induce cytoplasmic FUS aggregations, contributing to the neurodegenerative disease amyotrophic lateral sclerosis (ALS) in certain cases. While FUS is mainly a nuclear protein involved in transcriptional processes with limited cytoplasmic functions, it sho...
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| Publicado no: | Front Cell Neurosci |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6582137/ https://ncbi.nlm.nih.gov/pubmed/31244613 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2019.00256 |
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