Super-Resolution Microscopy Reveals Presynaptic Localization of the ALS/FTD Related Protein FUS in Hippocampal Neurons

Fused in Sarcoma (FUS) is a multifunctional RNA-/DNA-binding protein, which is involved in the pathogenesis of the neurodegenerative disorders amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). A common hallmark of these disorders is the abnormal accumulation of mutated FUS prote...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Schoen, Michael, Reichel, Jochen M., Demestre, Maria, Putz, Stefan, Deshpande, Dhruva, Proepper, Christian, Liebau, Stefan, Schmeisser, Michael J., Ludolph, Albert C., Michaelis, Jens, Boeckers, Tobias M.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4709451/
https://ncbi.nlm.nih.gov/pubmed/26834559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2015.00496
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