Electrophysiological properties of iPS cell-derived cardiomyocytes from a patient with long QT syndrome type 1 harboring the novel mutation M437V of KCNQ1

INTRODUCTION: Long QT syndrome type 1 (LQT1) is caused by mutations in KCNQ1 coding slowly-activating delayed-rectifier K(+) channels. We identified the novel missense mutation M437V of KCNQ1 in a LQT1 patient. Here, we employed iPS cell (iPSC)-derived cardiomyocytes to investigate electrophysiologi...

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Publicat a:Regen Ther
Autors principals: Sogo, Tatsufumi, Morikawa, Kumi, Kurata, Yasutaka, Li, Peili, Ichinose, Takafumi, Yuasa, Shinsuke, Nozaki, Daizou, Miake, Junichiro, Ninomiya, Haruaki, Shimizu, Wataru, Fukuda, Keiichi, Yamamoto, Kazuhiro, Shirayoshi, Yasuaki, Hisatome, Ichiro
Format: Artigo
Idioma:Inglês
Publicat: Japanese Society for Regenerative Medicine 2016
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6581809/
https://ncbi.nlm.nih.gov/pubmed/31245483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.reth.2015.12.001
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