Inhibitory effects of class I antiarrhythmic agents on Na(+) and Ca(2+) currents of human iPS cell-derived cardiomyocytes

INTRODUCTION: Human induced pluripotent stem cells (hiPSCs) harboring cardiac myosin heavy chain 6 promoter can differentiate into functional cardiomyocytes called “iCell cardiomyocytes” under blasticidin treatment condition. While iCell cardiomyocytes are expected to be used for predicting cardioto...

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Detalhes bibliográficos
Publicado no:Regen Ther
Main Authors: Yonemizu, Sayaka, Masuda, Keiichiro, Kurata, Yasutaka, Notsu, Tomomi, Higashi, Yuhei, Fukumura, Kenta, Li, Peili, Ninomiya, Haruaki, Miake, Junichiro, Tsuneto, Motokazu, Shirayoshi, Yasuaki, Hisatome, Ichiro
Formato: Artigo
Idioma:Inglês
Publicado em: Japanese Society for Regenerative Medicine 2019
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6360514/
https://ncbi.nlm.nih.gov/pubmed/30766898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.reth.2018.12.002
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