Molecularly Distinct Clathrin-Coated Pits Differentially Impact EGFR Fate and Signaling

Adaptor protein 2 (AP2) is a major constituent of clathrin-coated pits (CCPs). Whether it is essential for all forms of clathrin-mediated endocytosis (CME) in mammalian cells is an open issue. Here, we demonstrate, by live TIRF microscopy, the existence of a subclass of relatively short-lived CCPs l...

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Gepubliceerd in:Cell Rep
Hoofdauteurs: Pascolutti, Roberta, Algisi, Veronica, Conte, Alexia, Raimondi, Andrea, Pasham, Mithun, Upadhyayula, Srigokul, Gaudin, Raphael, Maritzen, Tanja, Barbieri, Elisa, Caldieri, Giusi, Tordonato, Chiara, Confalonieri, Stefano, Freddi, Stefano, Malabarba, Maria Grazia, Maspero, Elena, Polo, Simona, Tacchetti, Carlo, Haucke, Volker, Kirchhausen, Tom, Di Fiore, Pier Paolo, Sigismund, Sara
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cell Press 2019
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6581797/
https://ncbi.nlm.nih.gov/pubmed/31167147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.05.017
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