Reticulon3-dependent ER-PM contact sites control EGFR non-clathrin endocytosis

The integration of endocytic routes is critical to regulate receptor signaling. A non-clathrin endocytic pathway (NCE) of the epidermal growth factor receptor (EGFR) is activated at high ligand concentrations and targets receptors to degradation, attenuating signaling. Here we performed an unbiased...

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Bibliografske podrobnosti
izdano v:Science
Main Authors: Caldieri, Giusi, Barbieri, Elisa, Nappo, Gilda, Raimondi, Andrea, Bonora, Massimo, Conte, Alexia, Verhoef, Lisette G.G.C., Confalonieri, Stefano, Malabarba, Maria Grazia, Bianchi, Fabrizio, Cuomo, Alessandro, Bonaldi, Tiziana, Martini, Emanuele, Mazza, Davide, Pinton, Paolo, Tacchetti, Carlo, Polo, Simona, Di Fiore, Pier Paolo, Sigismund, Sara
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5432029/
https://ncbi.nlm.nih.gov/pubmed/28495747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aah6152
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