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Reticulon3-dependent ER-PM contact sites control EGFR non-clathrin endocytosis
The integration of endocytic routes is critical to regulate receptor signaling. A non-clathrin endocytic pathway (NCE) of the epidermal growth factor receptor (EGFR) is activated at high ligand concentrations and targets receptors to degradation, attenuating signaling. Here we performed an unbiased...
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| Gepubliceerd in: | Science |
|---|---|
| Hoofdauteurs: | , , , , , , , , , , , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2017
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5432029/ https://ncbi.nlm.nih.gov/pubmed/28495747 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aah6152 |
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