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Analysis of human mitochondrial DNA content by Southern blot and non-radioactive probe hybridization: A Southern blot and non-radioactive probe hybridization method to estimate human mitochondrial DNA content

A single cell can contain several thousand copies of the mitochondrial DNA genome or mtDNA. Tools for assessing mtDNA content are necessary for clinical and toxicological research as mtDNA depletion is linked to genetic disease and drug toxicity. For instance, mtDNA depletion syndromes are typically...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Curr Protoc Toxicol
Päätekijät: Wheeler, Joel H., Young, Carolyn K. J., Young, Matthew J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6581606/
https://ncbi.nlm.nih.gov/pubmed/30982231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cptx.75
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