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Analysis of human mitochondrial DNA content by Southern blot and non-radioactive probe hybridization: A Southern blot and non-radioactive probe hybridization method to estimate human mitochondrial DNA content

A single cell can contain several thousand copies of the mitochondrial DNA genome or mtDNA. Tools for assessing mtDNA content are necessary for clinical and toxicological research as mtDNA depletion is linked to genetic disease and drug toxicity. For instance, mtDNA depletion syndromes are typically...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Curr Protoc Toxicol
Prif Awduron: Wheeler, Joel H., Young, Carolyn K. J., Young, Matthew J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6581606/
https://ncbi.nlm.nih.gov/pubmed/30982231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cptx.75
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