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Analysis of human mitochondrial DNA content by Southern blot and non-radioactive probe hybridization: A Southern blot and non-radioactive probe hybridization method to estimate human mitochondrial DNA content
A single cell can contain several thousand copies of the mitochondrial DNA genome or mtDNA. Tools for assessing mtDNA content are necessary for clinical and toxicological research as mtDNA depletion is linked to genetic disease and drug toxicity. For instance, mtDNA depletion syndromes are typically...
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| Publicado no: | Curr Protoc Toxicol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6581606/ https://ncbi.nlm.nih.gov/pubmed/30982231 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cptx.75 |
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