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Posttreatment Effect of MGMT Methylation Level on Glioblastoma Survival
The DNA repair protein O6-methylguanine-DNA methyltransferase (MGMT) removes temozolomide-induced alkylation, thereby preventing DNA damage and cytotoxicity. We investigated the prognostic effect of different MGMT methylation levels on overall and progression-free survival in 327 patients with prima...
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| Publicado no: | J Neuropathol Exp Neurol |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6581556/ https://ncbi.nlm.nih.gov/pubmed/31058280 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnen/nlz032 |
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