Posttreatment Effect of MGMT Methylation Level on Glioblastoma Survival

The DNA repair protein O6-methylguanine-DNA methyltransferase (MGMT) removes temozolomide-induced alkylation, thereby preventing DNA damage and cytotoxicity. We investigated the prognostic effect of different MGMT methylation levels on overall and progression-free survival in 327 patients with prima...

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Bibliografiske detaljer
Udgivet i:J Neuropathol Exp Neurol
Main Authors: Dahlrot, Rikke H, Larsen, Pia, Boldt, Henning B, Kreutzfeldt, Melissa S, Hansen, Steinbjørn, Hjelmborg, Jacob B, Kristensen, Bjarne Winther
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2019
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Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6581556/
https://ncbi.nlm.nih.gov/pubmed/31058280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnen/nlz032
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