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(31)P and (1)H NMR investigation of the structure of the phosphorylating intermediates in the phosphodiester approach to the oligonucleotide synthesis

The structure of the reactive phosphorylating derivatives (B) formed by treatment of pdT(Ac) and of the model compound phenylphosphate with condensing reagents in pyridine was studied. Using γ-picoline instead of pyridine it was demonstrated by phosphorus and proton NMR spectroscopy that B contains...

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Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Nucleic Acids Res
Κύριοι συγγραφείς: Zarytova, V.F., Graifer, D.M., Ivanova, E.I., Knorre, D.G., Lebedev, A.V., Rezvukhin, A.I.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Oxford University Press 1978
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6581364/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/1.suppl_1.s209
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