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Evaluation of SYA16263 as a new potential antipsychotic agent without catalepsy.
SYA16263 exhibited moderate radioligand binding affinity at the D(2) receptor and produced inhibition of apomorphine-induced climbing behavior in mice with an ED(50) value of 3.88 mg/kg IP, predicting potential antipsychotic effects in humans. Analysis of plasma and brains from rats injected IP with...
Gorde:
| Argitaratua izan da: | Pharmacol Biochem Behav |
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| Egile Nagusiak: | , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2019
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6581196/ https://ncbi.nlm.nih.gov/pubmed/30768942 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbb.2019.02.003 |
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