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Evaluation of the potential of antipsychotic agents to induce catalepsy in rats: Assessment of a new, commercially available, semi-automated instrument
Haloperidol induced catalepsy was determined using the classic bar test and a new MED Associates Catalepsy Test Chamber instrument. The dose that produced an adverse effect in 50% of rats (AED(50)) for haloperidol was calculated using the instrument data as 0.29 mg/kg. Hand scoring of the video reco...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3992273/ https://ncbi.nlm.nih.gov/pubmed/24565832 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbb.2014.02.013 |
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