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Evaluation of the potential of antipsychotic agents to induce catalepsy in rats: Assessment of a new, commercially available, semi-automated instrument

Haloperidol induced catalepsy was determined using the classic bar test and a new MED Associates Catalepsy Test Chamber instrument. The dose that produced an adverse effect in 50% of rats (AED(50)) for haloperidol was calculated using the instrument data as 0.29 mg/kg. Hand scoring of the video reco...

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Detalhes bibliográficos
Main Authors: Bricker, Barbara, Sampson, Dinithia, Ablordeppey, Seth Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3992273/
https://ncbi.nlm.nih.gov/pubmed/24565832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbb.2014.02.013
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