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Identification of A Butyrophenone Analog as a Potential Atypical Antipsychotic Agent: 4-[4-(4-Chlorophenyl)-1,4-diazepan-1-yl]-1-(4-fluorophenyl)butan-1-one

The synthesis and exploration of novel butyrophenones have led to the identification of a diazepane analog of haloperidol, 4-[4-(4-Chlorophenyl)-1,4-diazepan-1-yl]-1-(4-fluorophenyl)butan-1-one (Compound 13) with an interesting multireceptor binding profile. Compound 13 was evaluated for its binding...

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Detalhes bibliográficos
Principais autores: Ablordeppey, Seth Y., Altundas, Ramazan, Bricker, Barbara, Zhu, Xue Y., Eyunni, Suresh E. V. K., Jackson, Tanise, Khan, Abdul, Roth, Bryan L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2664318/
https://ncbi.nlm.nih.gov/pubmed/18595716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2008.06.030
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