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Replication of Marek's Disease Virus Is Dependent on Synthesis of De Novo Fatty Acid and Prostaglandin E(2)

Marek’s disease virus (MDV) causes deadly lymphoma and induces an imbalance of the lipid metabolism in infected chickens. Here, we discovered that MDV activates the fatty acid synthesis (FAS) pathway in primary chicken embryo fibroblasts (CEFs). In addition, MDV-infected cells contained high levels...

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Bibliografiska uppgifter
I publikationen:J Virol
Huvudupphovsmän: Boodhoo, Nitish, Kamble, Nitin, Kaufer, Benedikt B., Behboudi, Shahriar
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2019
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6580946/
https://ncbi.nlm.nih.gov/pubmed/30971474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00352-19
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