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De Novo Cholesterol Biosynthesis and Its Trafficking in LAMP-1-Positive Vesicles Are Involved in Replication and Spread of Marek’s Disease Virus

Marek’s disease virus (MDV) transforms CD4(+) T cells and causes a deadly neoplastic disease that is associated with metabolic dysregulation leading to atherosclerosis in chickens. While MDV-infected chickens have normal serum concentrations of cholesterol, their aortic tissues were found to have el...

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Vydáno v:J Virol
Hlavní autoři: Boodhoo, Nitish, Kamble, Nitin, Behboudi, Shahriar
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7925193/
https://ncbi.nlm.nih.gov/pubmed/32999035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01001-20
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