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Replication of Marek's Disease Virus Is Dependent on Synthesis of De Novo Fatty Acid and Prostaglandin E(2)

Marek’s disease virus (MDV) causes deadly lymphoma and induces an imbalance of the lipid metabolism in infected chickens. Here, we discovered that MDV activates the fatty acid synthesis (FAS) pathway in primary chicken embryo fibroblasts (CEFs). In addition, MDV-infected cells contained high levels...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Boodhoo, Nitish, Kamble, Nitin, Kaufer, Benedikt B., Behboudi, Shahriar
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6580946/
https://ncbi.nlm.nih.gov/pubmed/30971474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00352-19
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