SU5416 does not attenuate early RV angiogenesis in the murine chronic hypoxia PH model

BACKGROUND: Right ventricular (RV) angiogenesis has been associated with adaptive myocardial remodeling in pulmonary hypertension (PH), though molecular regulators are poorly defined. Endothelial cell VEGFR-2 is considered a “master regulator” of angiogenesis in other models, and the small molecule...

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Detalhes bibliográficos
Publicado no:Respir Res
Main Authors: Peloquin, Grace L., Johnston, Laura, Damarla, Mahendra, Damico, Rachel L., Hassoun, Paul M., Kolb, Todd M.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6580559/
https://ncbi.nlm.nih.gov/pubmed/31208454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-019-1079-x
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